BPC-157 vs TB-500

Two different molecules from two different origins, frequently discussed together. Here is what separates them.

These two come up together constantly, usually because both appear in tissue-repair research literature. They are not variants of each other. They are structurally unrelated molecules from different origins.

What each one is

BPC-157

A synthetic pentadecapeptide, a chain of 15 amino acids. The sequence derives from a protein identified in gastric juice, which is where the name comes from: Body Protection Compound. It has been investigated in tissue-repair and gastrointestinal research.

TB-500

A synthetic fragment of thymosin beta-4, a naturally occurring protein found widely in human and animal cells. TB-500 represents the active region of that larger protein rather than the whole molecule. It has been investigated in recovery and repair research.

Side by side

Practical differences

From a handling point of view there is very little between them. Both arrive as lyophilised powder in 10mg vials, both reconstitute with bacteriostatic water the same way, and both store identically: refrigerated once mixed, never frozen in solution.

The only practical differences are price and the fact that they are different molecules.

Why they are discussed together

Because both appear in the same body of tissue-repair literature, not because they are related. They have distinct structures, distinct origins and distinct described mechanisms. Being studied in the same research area does not make two compounds interchangeable.

Common questions

What is the difference between BPC-157 and TB-500?

They are different molecules from different origins. BPC-157 is a synthetic pentadecapeptide, a 15 amino acid sequence derived from a protein found in gastric juice. TB-500 is a synthetic fragment of thymosin beta-4, a naturally occurring protein. Both have been investigated in tissue-repair research, which is why they are often discussed together.

Are they the same class of compound?

No. BPC-157 is a peptide fragment of a gastric protein; TB-500 is a fragment of thymosin beta-4. They are structurally unrelated and act through different described mechanisms in the research literature.

How are they supplied?

Both are supplied by Evra as 10mg lyophilised vials. BPC-157 is $100 and TB-500 is $120.

Do they reconstitute differently?

No. Both are lyophilised powders in 10mg vials and reconstitute the same way with bacteriostatic water. See the reconstitution calculator.

Which should I choose?

Both are supplied for laboratory research. If you have questions about either, message the team on Telegram.

Product pages: BPC-157 · TB-500